10. Phlebology in French-speaking Africa. Diagnostic features and associated factors at occurrence of post-thrombotic syndrome in the city of Ouagadougou, Burkina Faso. Diagnostic features and associated factors at the occurrence of post-thrombotic syndrome in the city of Ouagadougou.

Introduction: Post-thrombotic syndrome (PTS) or post- phlebitic disease (PPM) is the most common chronic complication of deep vein thrombosis. It is defined as the set of clinical manifestations of chronic venous insufficiency occurring in the medium or long term after deep vein thrombosis (DVT). Little study exists in the literature on the evolutionary modalities of DVT in the city of Ouagadougou. Objective: To determine the frequency and factors associated with the occurrence of post-thrombotic syndrome. Patients and methods: This was a descriptive and analytical cross-sectional study of patients who had had DVT for at least 06 months. The patients were reviewed and underwent a complete clinical examination with venous Doppler ultrasound of the lower limbs. The diagnostic criteria were based on the Villalta scale and venous Doppler echo data. We performed a bivariate analysis looking for factors associated with the occurrence of PTS. Results: We were able to recruit 89 patients, the mean age was 54.18 ± 13.73 years with extremes of 21 and 83 years. We found a slight female predominance of 52.81% with a sex ratio of 0.89. The prevalence of PTS was 67.94% with a mean time to onset of 27.78 months after the last episode of DVT. According to VILLALTA’s classification, we had 30.53% mild PTS, 28.24% moderate PTS, and 9.16% severe PTS. Functional and physical signs were dominated by cramps (89.89%) and pretibial edema (100%), respectively, with 10.11% venous ulcer. On ultrasound, the most frequent signs were: persistent thrombus (32.58%) and sequestration (29.21%) located in the common femoral vein. Anticoagulation, postural drainage and hygienic dietary measures were initiated in 88 patients, or 98.88%. Only 21% had good treatment adherence. Factors linked to the onset of PTS were obesity (OR = 8.45; p = 0.01), HRV thrombosis (OR = 8.34; p < 0.01), ATCD MTEV (OR = 8, 66; p = 0.02) and therapeutic non-compliance (OR = 7.38; p <0.01). Conclusion: PTS is frequent in patients with ATCD of DVT in the city of Ouagadougou. It is clinically manifested by cramps and pretibial edema, while the presence of sequests and the persistence of the thrombus are the main signs on venous Doppler echo. Factors associated with the onset of PTS are obesity, thrombosis of HRV and non-compliance with DVT.